RNA Details
Disease Name
myocardical ischemia
Tissue
heart
RNA Symbol
mir-146a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
NA
Target
NA
Pathway
VEGF SIGNALING PATHWAY
PubMed ID
Title
Exogenous miRNA-146a Enhances the Therapeutic Efficacy of Human Mesenchymal Stem Cells by Increasing Vascular Endothelial Growth Factor Secretion in the Ischemia/Reperfusion-Injured Heart
Year
2017
Function
"These data suggest that miR-146 is a novel miRNA that regulates VEGF expression, and its use may be an effective strategy for enhancing the therapeutic efficacy of human mesenchymal stem cells transplantation into the i/r-injured heart."